Long noncoding RNA SChLAP1 forms a growth promoting complex with HNRNPL in human glioblastoma through stabilization of ACTN4 and activation of NF- κB signaling.

CONCLUSIONS: Our results implicated SChLAP1 as a driver of GBM growth as well as a potential therapeutic target in treatment of the disease.
PMID: 31492748 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - September 5, 2019 Category: Cancer & Oncology Authors: Ji J, Xu R, Ding K, Bao G, Zhang X, Huang B, Wang X, Martinez A, Wang X, Li G, Miletic H, Thorsen F, Bjerkvig R, Xiang L, Han B, Chen A, Li XG, Wang J Tags: Clin Cancer Res Source Type: research