Extracorporeal Resuscitation with Carbon Monoxide Improves Renal Function by Targeting Inflammatory Pathways in Cardiac Arrest in Pigs.

CONCLUSION: Our data demonstrates improved renal function by extracorporeal CO treatment in a porcine model of cardiac arrest. CO reduced pro-inflammatory and pro-apoptotic signaling, characterizing beneficial aspects of a novel treatment option to overcome high mortality.
PMID: 31482730 [PubMed - as supplied by publisher]

Source: American Journal of Physiology. Renal Physiology - September 3, 2019 Category: Physiology Authors: Wollborn J, Schlueter B, Steiger C, Hermann C, Wunder C, Schmidt J, Diel P, Meinel L, Buerkle H, Goebel U, Schick MA Tags: Am J Physiol Renal Physiol Source Type: research