144 Increased lipid peroxidation in patients with skin lesions associated with human papillomavirus infection

Human papillomavirus (HPV) presents tropism for the skin and mucous membranes and produces a variety of afflictions. There are available many studies on the role of oxidative stress in HPV-associated cervical cancer; however data on cutaneous lesions is scarce. In recent years, it has been highlighted that lipid peroxidation is an important step in the pathogenesis of many diseases. We have enrolled 26 patients with palmoplantar warts, 15 patients with genital warts and 28 healthy subjects. To determine the level of lipid peroxidation we have measured the serum levels of 4-hydroxynonenal (4-HNE) by ELISA method.

Source: Journal of Investigative Dermatology - August 31, 2019 Category: Dermatology Authors: C.I. Mitran, M.I. Mitran, M. Tampa, I. Nicolae, M. Sarbu, C. Matei, S.R. Georgescu, M.I. Popa Tags: Clinical Research and Epidemiology Source Type: research