204 TRPV3 is highly activated in keratinocytes from patients with atopic dermatitis and contributes to warmth-evoked pruritogens release and itch behaviors

In this study, we investigated the relation between TRPV3 and warmth-evoked itch in AD. Here, we found a marked upregulation of TRPV3 in AD-lesional skin compared with healthy skin or lesional skin of psoriasis or allergic contact dermatitis.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Epidermal Structure and Function Source Type: research