A Comprehensive, Multidisciplinary, Precision Medicine Approach to Discover Effective Therapy for an Undiagnosed, Progressive, Fibro-inflammatory Disease

This report addresses the role of personalized medicine in identifying effective therapy for an undiagnosed disease. A 22-year old woman presented with chronic severe recurrent trismus, facial pain, progressive multicentric inflammatory and fibrotic masses, and high C-reactive protein. Sites of disease included the pterygomaxillary region, masseter muscles, mandible, lung, pericardium, intrabdominal cavity, and retroperitoneum.

Source: Translational Research - August 27, 2019 Category: Research Authors: Bernadette R. Gochuico, Shira G. Ziegler, Nicholas S. Ten, Nicholas J. Balanda, Christopher E. Mason, Paul Zumbo, Colleen A. Evans, Carter Van Waes, William A. Gahl, May Christine V. Malicdan Source Type: research