Midlife Smaller and Larger Infarctions, White Matter Hyperintensities, and 20-Year Cognitive Decline: A Cohort Study.

Conclusion: The substantial cognitive decline from middle age associated with having both smaller and larger infarctions, but not larger infarctions alone, suggests that the combination of smaller and larger infarctions may escalate risk for cognitive decline later in life in stroke-free persons. Primary Funding Source: National Institutes of Health. PMID: 31450238 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31450238?dopt=Abstract

Source: Annals of Internal Medicine - August 26, 2019 Category: Internal Medicine Authors: Windham BG, Griswold ME, Wilkening SR, Su D, Tingle J, Coker LH, Knopman D, Gottesman RF, Shibata D, Mosley TH Tags: Ann Intern Med Source Type: research