Intrinsic expression of viperin regulates thermogenesis in adipose tissues [Immunology and Inflammation]

Viperin is an interferon (IFN)-inducible multifunctional protein. Recent evidence from high-throughput analyses indicates that most IFN-inducible proteins, including viperin, are intrinsically expressed in specific tissues; however, the respective intrinsic functions are unknown. Here we show that the intrinsic expression of viperin regulates adipose tissue thermogenesis, which is known to counter...

Source: Proceedings of the National Academy of Sciences - August 26, 2019 Category: Science Authors: John Eom, Jeong Jin Kim, Seul Gi Yoon, Haengdueng Jeong, Soojin Son, Jae Bong Lee, Jihye Yoo, Hyun Ju Seo, Yejin Cho, Ku Sul Kim, Kyung Mi Choi, Il Yong Kim, Hui-Young Lee, Ki Taek Nam, Peter Cresswell, Je Kyung Seong, Jun-Young Seo Tags: PNAS Plus Source Type: research