Perinodular Vascularity Distinguishes Benign Intrapulmonary Lymph Nodes From Lung Cancer on Computed Tomography
Purpose: A common diagnostic dilemma in the assessment of small pulmonary nodules on computed tomography (CT) is in distinguishing benign intrapulmonary lymph nodes (IPLNs) from small primary pulmonary malignancies. Several CT features have been described of IPLNs, including attachment to a pleural surface. We had observed that IPLNs were often connected to a pulmonary vein and sought to evaluate the utility of this sign in discriminating IPLNs from lung adenocarcinomas. The frequency of other previously described CT signs of IPLNs was also compared with lung adenocarcinomas. Materials and Methods: We retrospectively identified histopathologically proven benign IPLNs (n=62) and small (
Conclusions: Inter-observer measurement variability for solid size was larger than for total size in lung adenocarcinoma. Large variability in group I indicated the difficulty of size measurement for low-grade malignant potential nodules such as adenocarcinoma in situ, minimally invasive adenocarcinoma, and early-stage invasive adenocarcinoma. The possibility of unavoidable size measurement variability should be recognized when deciding on surgical procedures for these diseases. PMID: 31463121 [PubMed]
ConclusionThe iodine quantification parameters derived from enhanced DE-CT during the VP may be useful for distinguishing lung squamous cell carcinoma from adenocarcinoma.
CONCLUSIONUsing 3D-MDCT, we could accurately divide A4 + 5 and safely perform the surgery.
We report a rare case of pulmonary IVLBCL accompanying lung cancer and interstitial lesions. A 73-year-old man with a history of pneumonia underwent a follow-up examination. Computed tomography revealed diffuse, bilateral ground-glass opacities (GGO) with a partial solid mass. Histologically, the mass consisted of adenocarcinoma. However, two other types of interstitial lesions were scattered throughout the resected lung: 1) peribronchovascular thickening with the aggregation of macrophages and anthracosis, and 2) alveolar septal thickening in the centrilobular area with atypical CD20-positive large cells in the capillarie...
The maximum standardized uptake value (SUVmax) on positron emission tomography with [18 F] fluorodeoxyglucose (18 F-FDG PET) is a promising modality for predicting the prognosis and invasiveness of lung adenocarcinoma. [1,2] Especially in cases where tumors had pure-solid appearances on thin-section CT scans, the SUVmax on PET reflected the levels of tumor invasiveness and had a g reat effect on the prognoses.  The SUVmax has been shown to be associated with histology in lung cancer. The low SUVmax levels correlated well with lepidic predominance among clinical stage IA radiologic pure-solid lung adenocarcinoma patients.
ConclusionsPET/CT, as a non-invasive method, can be preferred as the first choice in the detection of primary tumor in patients with BMUO.ResumenObjetivoEste trabajo analiza el papel de la PET/TC con 18F-FDG en la detección del tumor primario en pacientes con metástasis óseas de origen desconocido (MOOD).Material y MétodosEste estudio retrospectivo consideró al análisis histopatológico o el seguimiento clínico como datos de referencia en el diagnóstico de tumores primarios y estos resultados fueron comparados con los resultados de la PET/TC.ResultadosSe incluye...
Ground glass nodule (GGN) is defined as a hazy increased opacity of the lung, with preservation of the bronchial and vascular margins, and the diameter is less than 3 cm (1). With the wide spread of computed tomography (CT) screening, more and more lung nodules with a ground glass opacity(GGO) component have been identified (2–4). And we will meet some GGN cases more than 3 cm occasionally. To our knowledge, few previous studies as of yet had focused on th e GGO exceeding 3 cm. Our study dedicatedly included GGO more than 3 cm, and we named it ground glass mass (GGM)>3 cm firstly.
ConclusionSurgical treatment should be considered for pancreatic metastasis from lung cancer if the disease is localized and the patient’s condition is good. Additionally, combined therapy, including surgical resection, may be effective for repeated recurrence.
Publication date: August 2019Source: The Annals of Thoracic Surgery, Volume 108, Issue 2Author(s): Joji Samejima, Hiroyuki Ito, Haruhiko Nakayama, Takuya Nagashima, Junichiro Osawa, Kenji Inafuku, Masaki Suzuki, Tomoyuki Yokose, Kouzo Yamada, Munetaka MasudaBackgroundIn the Eighth Edition of the Tumor Node Metastasis Classification System for Lung Cancer, the definitions of the clinical T and pathologic T descriptors have changed. Little has been reported on comparisons between the consolidation diameter in the lung window setting and the tumor diameter in the mediastinal window setting with respect to the correlations wit...
Conclusion :18F-FDG PET/CT metabolic parameters combined with clinicopathological data demonstrated moderate diagnostic efficacy in predicting EGFR mutation status and were associated with prognosis in mutant and wild-type EGFR non-small-cell lung cancer, thus providing a reference for individualized targeted molecular therapy.