Lysyl oxidase —a possible role in systemic sclerosis–associated pulmonary hypertension: a multicentre study

ConclusionSerum LOX levels are increased in established SSc and inversely correlate with the DLCO. LOX is elevated in patients with moderate to severe PAH and is located in the proliferating endothelium in lung arterioles, suggesting a possible role for LOX in SSc-associated PAH.
Source: Rheumatology - Category: Rheumatology Source Type: research