The MicroRNA Cluster of MiR-15a, MiR-27a, and MiR-92a Is Associated With Diminished Interleukin 10 Levels and Decreased Frequency and Immune Suppressor Function of Type 1 Regulatory T Cells in Patients With Abdominal Aortic Aneurysms
MicroRNAs (miRNAs) play a key role in epigenetic dysregulation of immune responses in autoimmune diseases. However, their association with interleukin 10 (IL-10) expression and type 1 regulatory T cell (Tr1) function in patients with abdominal aortic aneurysm (AAA) has yet to be defined.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Justin R. King, Linden A. Green, Katherin Leckie, Keisin S. Wang, Praveen Kusumanchi, John G. Maijub, Andres Fajardo, Raghu L. Motaganahalli, Michael P. Murphy Tags: Abstract from the 2019 Midwestern Vascular Surgical Society Annual Meeting Source Type: research