Interaction of genetic variations in < i > NFE2L2 < /i > and < i > SELENOS < /i > modulates the risk of Hashimoto's thyroiditis.

Conclusions:</b> The <i>NFE2L2 </i>promoter genotype interacts with the <i>SELENOS </i>promoter genotype to modulate the risk of HT in a Portuguese population. This interaction may be due to a bidirectional positive feedback between the Nrf2 and SelS pathways. PMID: 31426718 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research