Primary upper pole liposarcoma of the kidney with invasion to inferior vena cava: a case report

Publication date: Available online 17 August 2019Source: Urology Case ReportsAuthor(s): Mehdi Kardoust Parizi, Solmaz Ohadian Moghadam, Seyed Ali MomeniAbstractGenitourinary tract liposarcoma is considered as the second most commonly reported type of sarcomas. Renal liposarcoma with tumor invasion to inferior vena cava (IVC) is distinctly rare. This tumor has a relatively indolent clinical course with risk of local recurrences (20%-85% rate) after surgery. Angiomyolipomas (AML) are the most important differential diagnosis because both are large fat-containing lesions. Herein, a patient with upper pole kidney liposarcoma with tumor invasion to renal vein and IVC is presented. The optimal management is radical nephrectomy and IVC tumor resection. Chemotherapy and radiotherapy have not shown significant survival benefit.
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research

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Publication date: Available online 26 August 2019Source: Clinical Lymphoma Myeloma and LeukemiaAuthor(s): Hyunkyung Park, Ja Min Byun, Youngil Koh, Sung-Soo Yoon, Hyejoo Park, Jayoun Lee, Sang-Jin Shin, Jeonghwan YoukAbstractBackgroundThe optimal the conditioning regimens for allogeneic hematopoietic stem-cell transplantation, especially for East Asian patients, remains unknown.Patients and MethodsWe collected and analyzed clinical and survival data of 4255 patients from the Korean National Health Insurance Claims Database.ResultsBetween 1562 myeloablative conditioning and 2693 nonmyeloablative conditioning groups, the ove...
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research
In this study, we developed a novel measurement system for these factors using a compact chemical luminescence immunological automatic analyzer POCubeTM. This assay system, which is based on the flow-through membrane immunoassay, completes the whole process and generates results within 15 min. Serum concentrations of these factors measured via POCubeTM correlated well with those measured using enzyme-linked immunosorbent assay (r = 0.994 for GDF15, r = 0.992 for progranulin, and r = 0.976 for osteopontin). The POCubeTM system provides rapid and easy measurement of these factors, thereby facilitating uterine sarcoma diagnos...
Source: Endocrine Journal - Category: Endocrinology Tags: Endocr J Source Type: research
CONCLUSIONS: Results should support a policy of strengthening medical doctors' capabilities to communicate with patients, providing them complete information and involving them in the clinical decisions. Specifically, the findings should be used to improve current provision of cancer care by identifying areas of preferred intervention from the perspectives of patients in order to tailor the service supply accordingly. PMID: 31535573 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Authors: Ohmoto A, Suzuki M, Takai E, Rokutan H, Fujiwara Y, Morizane C, Yanagihara K, Shibata T, Yachida S Abstract [This corrects the article DOI: 10.18632/oncotarget.24930.]. PMID: 31534635 [PubMed - in process]
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
In conclusion, results showed that adipose microenvironment can regulate the behavior of tumor and non tumor human renal epithelial cells. PMID: 31534630 [PubMed]
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Conclusions: Mortalin promotes cell proliferation, metastasis, angiogenesis, downregulate apoptotic signaling. Thus, mortalin is a potential therapeutic target for cancer immunotherapy. The novel SMRwt peptides antagonize the functions of mortalin, blocking tumor extracellular vesicle release and extracellular vesicle-mediated release of complement. This leads to decreases in breast cancer cell metastasis and allows standard treatment of these late stage tumor cells, thus having important clinical implications for late stage breast cancer chemotherapy. These findings support further investigation into the therapeutic value...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
We report a case of a 30 years old woman who underwent surgical resection for a well-differentiated liposarcoma. CT scan revealed that the mass invaded the left perirenal fascia and displaced the descending colon, pancreas, and duodenum. Complete resection of tumour masses were performed and we opted against nephrectomy due to the tumor's histologic type, the patient's young age, and increased morbidity.DiscussionTreatment for Retroperitoneal Liposarcoma involves R0 resection. In cases where the tumor invades into a nearby organ, it is necessary to weigh the benefit of free margin resection against the adversity of medical...
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
We report on a extremely rare case of asymptomatic perinephric dedifferentiated sclerosing liposarcoma which appeared to mimic cystic renal cell carcinoma on clinical and radiological presentation. The patient underwent a right partial nephrectomy and remains tumour free at six months follow up.
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research
We report on a extremely rare case of asymptomatic perinephric dedifferentiated sclerosing liposarcoma which appeared to mimic cystic renal cell carcinoma on clinical and radiological presentation. The patient underwent a right partial nephrectomy and remains tumour free at six months follow up.
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research
Conclusion Retroperitoneal liposarcoma has a high local recurrence rate due to the difficulty in complete surgical resection; therefore, additional hormone therapy is important for improving the prognosis.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
More News: Chemotherapy | Liposarcoma | Nephrectomy | Sarcomas | Urology & Nephrology