Hypomethylation of the IL8 promoter in nasal epithelial cells of patients with chronic rhinosinusitis with nasal polyps

IL-8 is an important chemokine implicated in the pathogenesis of chronic rhinosinusitis (CRS), but little is known about epigenetic regulation of IL8 in the pathogenesis of CRS.

Source: Journal of Allergy and Clinical Immunology - July 18, 2019 Category: Allergy & Immunology Authors: Jingyun Li, Jian Jiao, Ming Wang, Yunbo Gao, Ying Li, Yang Wang, Yuan Zhang, Xiangdong Wang, Luo Zhang Source Type: research