m5C Goes Viral.

m5C Goes Viral.
Cell Host Microbe. 2019 Aug 14;26(2):154-155
Authors: Winans S, Beemon K
Abstract
In this issue of Cell Host & Microbe, Courtney et al. (2019a) find that HIV-1 genomic RNA has much more m5C than cellular mRNA. Deleting the m5C "writer" NSUN2 decreases HIV-1 m5C levels, promotes translation of the HIV-1 5' gag gene, and alters splicing at the A2 site.
PMID: 31415745 [PubMed - in process]

Source: Cell Host and Microbe - August 13, 2019 Category: Microbiology Authors: Winans S, Beemon K Tags: Cell Host Microbe Source Type: research