A biased coin up-and-down sequential allocation trial to determine the optimum programmed intermittent epidural bolus time interval between 5 mL boluses of bupivacaine 0.125% with fentanyl 2 µg·mL −1

ConclusionThe EI90 between 5 mL boluses of bupivacaine 0.125% with fentanyl 2 µg·mL−1 during the first stage of labour is approximately 35 min.Trial registrationwww.clinicaltrials.gov (NCT #02758405); registered 2 May, 2016.

http://link.springer.com/10.1007/s12630-019-01407-7

Source: Canadian Journal of Anesthesia - August 15, 2019 Category: Anesthesiology Source Type: research