Thyroid peroxidase antibodies and prospective live birth - a cohort study of women with recurrent pregnancy loss.

CONCLUSION: In a large cohort of women with unexplained recurrent pregnancy loss, TPOAb-positivity was predictive of a reduced live birth rate. However, T4 treatment improved odds of live birth. The study supports screening for TPOAbs as a risk factor in women with unexplained recurrent pregnancy loss. The beneficial effect of T4 treatment in this high-risk group needs confirmation by randomized controlled trials. Close collaboration between fertility experts and endocrinologists is paramount. PMID: 31407629 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research