Strategies to Adjust Positive End-Expiratory Pressure in Patients With ARDS

To the Editor No benefit in death or days free from mechanical ventilation were reported with PES-guided PEEP titration vs an empirical high PEEP-Fio2 strategy in patients with moderate to severe ARDS. What was the racial/ethnic composition of the patients included in the 2 groups of the study, as significant racial/ethnic and sex differences in ARDS mortality exist in the United States? Also, significantly more men were in the PES-guided PEEP group than in the empirical high PEEP-Fio2 group (P  = .01).
Source: JAMA - Category: General Medicine Source Type: research