Interleukin ‐17A potentiates interleukin‐13‒induced eotaxin‐3 production by human nasal epithelial cells from patients with allergic rhinitis

ConclusionIL ‐17A potentiated IL‐13‒driven STAT6 activation through the downregulation of SOCS1 expression, leading to enhancement of eotaxin‐3 production by HNECs. These factors contributed to eosinophilic inflammation in AR.

Source: International Forum of Allergy and Rhinology - August 11, 2019 Category: Allergy & Immunology Authors: Wei Wei Wang, Kai Zhu, Hong Wei Yu, Yong Liang Pan Tags: ORIGINAL ARTICLE Source Type: research