Diabetes aggravates renal ischemia reperfusion injury by repressing mitochondrial function and PINK1/Parkin-mediated mitophagy.

CONCLUSION: Our results, for the first time, indicated that diabetes could aggravate I/R injury by repressing mitochondrial function and PINK1/Parkin-mediated mitophagy in vivo and in vitro. PMID: 31390235 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31390235?dopt=Abstract

Source: American Journal of Physiology. Renal Physiology - August 6, 2019 Category: Physiology Authors: Yang YY, Gong DJ, Zhang J, Liu X, Wang L Tags: Am J Physiol Renal Physiol Source Type: research