Axillary nodal involvement by primary tumor features in early breast cancer: an analysis of 2600 patients.

CONCLUSIONS: These results raise the question whether axillary node status is redundant in cases with exceptionally good features, i.e., small tumors with low Ki67, or in those candidate to adjuvant systemic treatment/radiotherapy anyway including TNBC, and support the incorporation of primary BC tumor characteristics as stratification factors in ongoing trials aiming at de-escalating axillary surgical procedures. PMID: 31372896 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31372896?dopt=Abstract

Source: Clinical Breast Cancer - July 31, 2019 Category: Cancer & Oncology Authors: De Santis MC, La Rocca E, Meneghini E, Bregni G, Di Lorenzo G, Galli G, Di Nicola M, Folli S, Gennaro M, Pruneri G, Paolini B, Daidone MG, De Braud F, Apolone G, Sant M, Di Cosimo S Tags: Clin Transl Oncol Source Type: research