High Glucose-Induced Downregulation of Connexin 30.2 Promotes Retinal Vascular Lesions: Implications for Diabetic Retinopathy [Retinal Cell Biology]

Conclusions. These results indicate that HG- or diabetes-induced downregulation of Cx30.2 expression and decrease in GJIC activity play a critical role in the development of retinal vascular lesions in early DR.

http://www.iovs.org/cgi/content/full/54/3/2361?rss=1

Source: Investigative Ophthalmology - March 28, 2013 Category: Opthalmology Authors: Manasson, J., Tien, T., Moore, C., Kumar, N. M., Roy, S. Tags: Retinal Cell Biology Source Type: research