Evaluation of an emergency department buprenorphine induction and medication-assisted treatment referral program

The objective of this study was to describe a pragmatic approach to buprenorphine induction, referral to treatment, and assess follow-up rates.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research

Related Links:

BACKGROUND: Community overdose responders do not always seek help from emergency services when administering naloxone. We aimed to identify responder, overdose event, and community characteristics associated with help seeking from emergency services during...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
BACKGROUND: Factors surrounding opioid overdose and naloxone use must be explored from the user perspective in order to more effectively combat the current opioid crisis. METHODS: AIDS Resource Center of Wisconsin needle exchange clients were surve...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Discussion: Despite a strong rationale for the use of TDM for oral anticancer drugs, this is currently not yet widely adopted in routine patient care. This prospective study will be a valuable contribution to demonstrate the additional value of dose optimization on treatment outcome for these drugs.
Source: Therapeutic Drug Monitoring - Category: Drugs & Pharmacology Tags: Focus Series: TDM in Oncology Source Type: research
Authors: Hosoda T, Uehara Y, Naito T Abstract Patients with HIV infection represent a high-risk group for medication overdose because of the high frequency of complicating psychiatric disorders. Raltegravir is well-known for its low frequency of adverse effects. We herein report a 42-year-old Japanese man with HIV infection who was hospitalized 6 hours after overdosing with 24,000 mg of raltegravir in a suicide attempt. No serious adverse events occurred, although the plasma concentration of raltegravir at 18 hours after the overdose was 79,871.1 ng/mL. Raltegravir may be well-indicated for HIV patients at risk of ...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
This article describes the implementation of an innovative nonfatal overdose response system delivered by peers in selected emergency departments in a major urban city.American Journal of Public Health
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Public Health & Prevention Journal Article Source Type: news
Conclusions: The risks of SA and SDO were proportionally increased by head injury in patients with depression in Taiwan. Our findings provide crucial information to implement efficient suicide prevention strategies in the future.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Acetaminophen (APAP) is an analgesic–antipyretic drug and widely used in clinics. Its overdose may cause serious liver damage. Here, we examined the mechanistic role of c-Jun N-terminal kinase (JNK) signaling pathway in liver injury induced by different doses of APAP. Male mice were treated with APAP (150 and 175 mg·kg−1), and meanwhile JNK inhibitor SP600125 was used to interfere APAP-induced liver damage. The results showed that JNK signaling pathway was activated by APAP in a dose-dependent manner. C-Jun N-terminal kinase inhibitor decreased JNK and c-Jun activation significantly (P
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Neuropediatrics DOI: 10.1055/s-0039-1695786A 6.5-year-old female patient with a TSC2 mutation had been given everolimus (EVE) for 3 years for pharmacoresistant focal epilepsy and for life-threatening, severe ventricular dysrhythmia. EVE had been started with daily dose of 0.15 mg/kg/day and was increased up to 0.6 mg/kg/day. Target blood trough levels of around 9 µg/L had been documented. Although EVE therapy revealed no effect on seizure activity, cardiac rhythm normalized completely. Thus, EVE was reduced to a dose of 0.3 mg/kg/day leading to stable blood trough levels of 4 to 5&t...
Source: Neuropediatrics - Category: Neurology Authors: Tags: Short Communication Source Type: research
QuickStats: Age-Adjusted Rates of Drug Overdose Deaths Involving Heroin,* by Race/Ethnicity† - National Vital Statistics System, United States, 1999-2017. MMWR Morb Mortal Wkly Rep. 2019 Sep 20;68(37):810 Authors: PMID: 31536483 [PubMed - in process]
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Tags: MMWR Morb Mortal Wkly Rep Source Type: research
Conclusions: Prescription of opioids after low acuity urology procedures is significantly associated with increased opioid use at 1 yr after surgery; efforts should be made to reduce postoperative opioids, especially for urologic procedures that do not typically require opioids.Patient summary: Filling an opioid prescription after minor urologic surgeries is associated with an increased risk of persistent long-term use of opioid medications and a higher risk of serious long-term complications such as hospital visits for an opioid overdose.’
Source: European Urology - Category: Urology & Nephrology Source Type: research
More News: Emergency Medicine | Overdose | Study