Delivery of bioactives in food for optimal efficacy: What inspirations and insights can be gained from pharmaceutics?

ConclusionsTo date, most literature focused on development of delivery systems, their loading performance, stability, protective effects, sensorial attributes and their effect on the bioavailability of the bioactives. Few studies start showing in vivo evidence for improved efficacy of the bioactives thanks to the delivery system. There still remains a need to ascertain that bioactive compounds delivered in real functional foods safely provide health benefits to the consumer. More in vivo and clinical studies are required to assure safety and provide bioavailability and efficacy results to support health claims. We highlight concepts which are common in drug delivery, but are completely new in food, like selective delivery to target-cells, or efflux pump-inhibition for improved uptake. Several possible future trends are suggested.

Source: Trends in Food Science and Technology - July 27, 2019 Category: Food Science Source Type: research