Role of vitamin D in influencing angiogenesis in preeclampsia.
Role of vitamin D in influencing angiogenesis in preeclampsia.
Hypertens Pregnancy. 2019 Jul 24;:1-7
Authors: Nema J, Sundrani D, Joshi S
Abstract
Objective: Vitamin D plays a key role during pregnancy and is involved in implantation and maintenance of pregnancy. Its deficiency is associated with pregnancy complications like preeclampsia, characterized by abnormal angiogenesis.Method: The current article summarises studies examining the role of vitamin D in pregnancy, with special emphasis on preeclampsia.Results and conclusion: An imbalance in pro- and anti-angiogenic factors is reported in women with preeclampsia. Cell culture studies have demonstrated that vitamin D can influence the process of angiogenesis. However, the role of maternal vitamin D in influencing placental angiogenesis in preeclampsia is unclear and needs to be explored.
PMID: 31340689 [PubMed - as supplied by publisher]
Source: Hypertension in Pregnancy - Category: OBGYN Tags: Hypertens Pregnancy Source Type: research
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