Low-dose naltrexone: a unique treatment for amyopathic dermatomyositis.

Low-dose naltrexone: a unique treatment for amyopathic dermatomyositis. Dermatol Online J. 2019 Jun 15;25(6): Authors: Manudhane AP, Schrom KP, Ezaldein HH, Armile JA Abstract Gottron papules, a heliotrope rash, scalp and extremity erythema, pruritus, and fatigue are the characteristic signs and symptoms of amyopathic dermatomyositis (ADM). Amyopathic dermatomyositis is considered a distinct entity from dermatomyositis (DM) because the characteristic muscle weakness and muscle enzyme elevations of DM are absent in ADM. With respects to treatment, ADM treatments have traditionally included topical corticosteroids and/or systemic immunosuppressants and immunomodulators. Herein we present a patient with refractory ADM that was responsive to low-dose naltrexone therapy. PMID: 31329393 [PubMed - in process]
Source: Dermatol Online J - Category: Dermatology Authors: Tags: Dermatol Online J Source Type: research