Basement membrane zone IgE deposition is associated with bullous pemphigoid disease severity and treatment results.

CONCLUSION: IgE deposition in the BMZ is associated with higher E/B BPDAI scores and longer treatment periods. We conclude that IgE binding in the BMZ may contribute to BP pathogenesis by promoting blister formation. This article is protected by copyright. All rights reserved. PMID: 31330562 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31330562?dopt=Abstract

Source: The British Journal of Dermatology - July 21, 2019 Category: Dermatology Authors: Kamata A, Kurihara Y, Funakoshi T, Takahashi H, Kuroda K, Hachiya T, Amagai M, Yamagami J Tags: Br J Dermatol Source Type: research