Feedback regulation of Arid5a and Ppar-{gamma}2 maintains adipose tissue homeostasis [Immunology and Inflammation]

Immune cells infiltrate adipose tissues and provide a framework to regulate energy homeostasis. However, the precise underlying mechanisms and signaling by which the immune system regulates energy homeostasis in metabolic tissues remain poorly understood. Here, we show that the AT-rich interactive domain 5A (Arid5a), a cytokine-induced nucleic acid binding protein,...

Source: Proceedings of the National Academy of Sciences - July 22, 2019 Category: Science Authors: Jaya Prakash Chalise, Shigeru Hashimoto, Gyanu Parajuli, Sujin Kang, Shailendra Kumar Singh, Yohannes Gemechu, Hozaifa Metwally, Kishan Kumar Nyati, Praveen Kumar Dubey, Mohammad Mahabub-Uz Zaman, Yasuharu Nagahama, Hanieh Hamza, Kazuya Masuda, Tadamitsu Tags: Biological Sciences Source Type: research