Adjuvant volumetric modulated arc therapy compared to 3d conformal radiation therapy for newly diagnosed soft tissue sarcoma of the extremities: outcome and toxicity evaluation.

CONCLUSION: The availability of modern radiotherapy technique permit a better conformity on the target with maximum sparing of normal tissue and acceptable side-effects. VMAT is a safe and feasible treatment with limited rate of toxicity, compared to 3DCRT. Results on LC of VMAT are encouraging. ADVANCES IN KNOWLEDGE: Soft tissue sarcoma of the extremities can benefit from the use of VMAT, with a reduction of the high dose to bones to avoid radiation osteonecrosis. An adequate total dose of at least 66 Gy and a radical surgical margin allow a good local control. PMID: 31322910 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31322910?dopt=Abstract

Source: The British Journal of Radiology - July 18, 2019 Category: Radiology Authors: Di Brina L, Fogliata A, Navarria P, D'Agostino GR, Franzese C, Franceschini D, De Rose F, Comito T, Bertuzzi A, Marrari A, Colombo P, Quagliuolo V, Santoro A, Scorsetti M Tags: Br J Radiol Source Type: research