Transfusion-related immune modulation: functional consequence of extracellular vesicles?

Transfusion-related immune modulation: functional consequence of extracellular vesicles? Transfusion. 2019 Jul 19;: Authors: Menocha S, Muszynski JA Abstract Extracellular vesicles (EVs) are small, subcellular vesicles that are released from a variety of cells and play important roles in cell-to-cell communication. Transfused blood products, including red blood cell, platelet, and plasma products contain EVs that are capable of interacting with and altering immune cell function. The extent to which EVs may contribute to clinically meaningful immunomodulatory effects of transfusion remains unclear and deserving of further study. PMID: 31322730 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31322730?dopt=Abstract

Source: Transfusion - July 18, 2019 Category: Hematology Authors: Menocha S, Muszynski JA Tags: Transfusion Source Type: research

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