Gene Therapy for Skin Fragility Diseases: The New Generation

Ex  vivo gene therapy is a promising approach to treat devastating skin fragility diseases. March et al. and Takashima et al. report that programmable nucleases—TALENs and CRISPR/Cas9—can safely and efficiently correct genetic defects in cultured adult skin cells, paving the way for broader clin ical applications of gene therapies in dermatology.

Source: Journal of Investigative Dermatology - July 19, 2019 Category: Dermatology Authors: Ganna Bilousova Tags: Commentary Source Type: research