Lipase inhibitory activity of skim milk fermented with different strains of lactic acid bacteria
Publication date: September 2019Source: Journal of Functional Foods, Volume 60Author(s): Ana María Gil-Rodríguez, Thomas P. BeresfordAbstractOne of the main causes of obesity is an imbalance between energy intake and expenditure. One approach to facilitate weight loss is to decrease absorption of energy-rich nutrients by inhibition of pancreatic lipase. A spectrophotometric method was developed to evaluate the potential of milk fermented with lactic acid bacteria to inhibit pancreatic lipase in vitro. Fermentates produced with Lactobacillus helveticus strains at 42 °C exhibited the highest levels of lipase inhibition, with strains SC8, SC44 and SC45 inhibiting pancreatic lipase by>49%, significantly higher than the activity of a milk control. In all cases activity was retained after removal of large proteins including casein and in the
The objective of this study was to measure gene expression of various preadipocyte, proliferation, metabolic, and apoptotic markers in the stromal-vascular fraction and adipocytes from LWS and HWS adipose tissue. Although preadipocyte and proliferation markers were more highly expressed in the stromal-vascular fraction of LWS than HWS chicks, greater expression of granzyme-A and the presence of more annexin V-positive cells suggests that apoptosis may limit the adipogenic potential of adipocyte precursor cells and represent a novel mechanism that regulates the expansion of adipose tissue. Results provide insights on cellul...
Authors: Öztürk H, Özen B, Çatlı G, Dündar B Abstract Background: Macular damage may be observed in obesity and metabolic syndrome (MetS) that lead to chronic subclinical inflammation and affect almost all organ systems. Objectives: The purpose of this study was to investigate the relations of macular variability with anthropometric measurements, metabolic parameters, and inflammatory markers in children and adolescents with MetS. Methods: Two hundred twenty-eyes of 62 obese and 48 healthy children and adolescents were included in the study. Bilateral macular retinal thickness (M...
Conclusion: Obesity prevalence of our T1D cohort is similar to healthy population in the same ages. Prevalence of MetS is higher in children and adolescents with T1D compared to the obese population in our country. Our study suggests that IDF criteria are more suitable for the diagnosis of MetS in children and adolescents with T1D. PMID: 31434460 [PubMed - as supplied by publisher]
AbstractAfrican Americans and ethnic minorities experience racial discrimination in a variety of settings. Racial discrimination is a potent stressor that has been linked to psychosocial stress and poor physical health. To cope with discriminatory experiences and daily life event stressors, African Americans frequently use the concept of John Henryism (a high effort coping strategy with prolonged exposure to stress). This cross-sectional analysis explored the relationship between racism/discrimination, John Henryism, and health problems in a predominately African American sample. Data were collected through health care scr...
Neck and back pain caused by intervertebral disc (IVD) degeneration is a frequent cause of referral to spine surgeons. This is a multifactorial disease process caused by aging, injury, obesity, and mechanical stress. Recently, an association between IVD degeneration and diabetes has been identified, but the mechanisms underlying this relationship are unclear. Furthermore, the effects of insulin levels on cytokines known to be elevated in diabetics have not previously been delineated. Uncontrolled diabetes results in chronic systemic inflammation with increased circulating levels of IL-6 and IL-18.
Bariatric surgery for morbid obesity helps to address common comorbidity burdens, including decreasing rates of myocardial infarction and stroke. The increased mechanical stresses on the spine caused by morbid obesity predispose patients to various spinal pathologies and are concerning for spinal surgeons, with previous studies suggesting poorer outcomes than the general population. The effects of bariatric surgery on diminishing spinal complaints or symptoms have yet to be elucidated in the literature.
Obese patients, particularly those with a body mass index (BMI) ≥35 kg/m2, pose a major challenge for a spine surgeon. Though obesity has previously been shown to be linked with adverse outcomes following elective spine surgical procedures, the impact of prior bariatric surgery on altering postoperative outcomes following elective anterior cervical discectomy and fusions (ACDFs) has not been explored.
Obesity has been shown to be associated with higher rates of complications following lumbar spine surgery. However, the evidence regarding the impact of increasing body mass index (BMI) on postoperative outcomes following posterior cervical fusions remains limited.
Obesity in the pediatric population is shown to be associated with adverse outcomes across varying specialties. The weight-outcome relationship in neuromuscular scoliosis has not been thoroughly investigated.
Previous research on the impact of obesity on outcomes after adult spinal deformity surgery has reported radiographic and clinical outcomes, but no analysis has compared the mental health status and outcomes in these patients.