Report: J & amp;J facing criminal investigation in ongoing talc scandal

The Department of Justice is reportedly investigating claims that Johnson and Johnson officials lied about cancer risks tied to its popular baby powder.
Source: - Category: Pharmaceuticals Source Type: news

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Publication date: 1 November 2019Source: Colloids and Surfaces B: Biointerfaces, Volume 183Author(s): Jian-Tao Lin, Hua Chen, Dan Wang, Liang Xiong, Jia-Zhu Li, Gui-hong Chen, Guang-Bin ChenAbstractThe nucleus is one of the most important cellular organelles. Chitosan-grafted poly-(N-3-carbobenzyloxy-lysine) (CCL) decorated with human immunodeficiency virus-1 transactivator of transcription (TAT) can co-deliver p53 and doxorubicin into the nucleus simultaneously, such that their antitumor functions are exerted. However, TAT-CCL has been shown to have an anti-tumor effect only in vitro; the effect in vivo was unsatisfactory...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
ConclusionsMen with mHNPC gain treatment benefit from ADT + AAP irrespective of risk stratification for “risk” or “volume”.Patient summaryCoadministration of abiraterone acetate and prednisolone with androgen deprivation therapy (ADT) is associated with prolonged overall survival and disease control, compared with ADT alone, in all men with metastatic disease starting hormone therapy for the first time.
Source: European Urology - Category: Urology & Nephrology Source Type: research
CONCLUSION: The glassy cell carcinoma of the cervix should be considered as an aetiology of bone metastases in young female patients. PMID: 31431320 [PubMed - as supplied by publisher]
Source: Revue de Medecine Interne - Category: Internal Medicine Tags: Rev Med Interne Source Type: research
ConclusionThe iodine quantification parameters derived from enhanced DE-CT during the VP may be useful for distinguishing lung squamous cell carcinoma from adenocarcinoma.
Source: Academic Radiology - Category: Radiology Source Type: research
Publication date: Available online 21 August 2019Source: Journal of the American Society of CytopathologyAuthor(s): Russel Fetzer, Michelle Duey, Valerie Pena, Dana Wanzer, James Kirkpatrick, Donnie Chau, Venetia R. SarodeAbstractIntroductionData on the performance of cytotechnologists in assessing specimen adequacy of needle core biopsies (NCB) is scant and their role in specimen triaging for ancillary studies have not been well established.Materials and methodsWe retrospectively analyzed ROSE performed exclusively by cytotechnologists on 248 NCB and fine needle aspiration (FNA) specimens. Overall adequacy and accuracy ra...
Source: Journal of the American Society of Cytopathology - Category: Cytology Source Type: research
Publication date: August 2019Source: Chinese Journal of Analytical Chemistry, Volume 47, Issue 8Author(s): Li-Ting NIU, Gen-Gen LI, Hai-Feng LI, Fan CUI, Jing ZHANG, Ying HUANG, Kai CHEN, Jian-Fu ZHANG, Wen-Fei LI, Wei-Lu LIUAbstractGenistein is an important isoflavone that has been widely used to prevent blood disease and cancer. In this work, a novel genistein electrochemical sensor was developed based on the composite of molecularly imprinted polymer (MIP) and carboxylated multiwalled carbon nanotubes (cMWCNTs). The MIP layer was electropolymerizated on the cMWCNTs modified electrode using carbazole as functional monome...
Source: Chinese Journal of Analytical Chemistry - Category: Chemistry Source Type: research
ConclusionThe combination of PHI and mpMRI had higher accuracy for detection of csPC compared with PHI or mpMRI alone in an Asian population.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
Conclusions: Our study indicates that solid nodules have the highest risk of malignancy. Furthermore, the cytological evaluation of subsolid and partially calcified nodules is crucial for the accurate diagnosis and appropriate clinical management of lung nodule patients.
Source: CytoJournal - Category: Pathology Authors: Source Type: research
Conclusion Treatment of CIED-patients with protons and carbon ions applied with active raster scanning technique was safe without any incidents in our single center experience. Monitoring after almost every fraction provided systematic and extensive data. Further investigations are necessary in order to form reliable guidelines, which should consider different modes of beam application, as active scanning supposedly provides a greater level of safety from malfunctions for patients with CIED undergoing particle irradiation.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Molecules, Vol. 24, Pages 3063: Untargeted Metabolomic Profile for the Detection of Prostate Carcinoma—Preliminary Results from PARAFAC2 and PLS–DA Models Molecules doi: 10.3390/molecules24173063 Authors: Amante Salomone Alladio Vincenti Porpiglia Bro Prostate-specific antigen (PSA) is the main biomarker for the screening of prostate cancer (PCa), which has a high sensibility (higher than 80%) that is negatively offset by its poor specificity (only 30%, with the European cut-off of 4 ng/mL). This generates a large number of useless biopsies, involving both risks for the patients and cost...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
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