Dynactin1 depletion leads to neuromuscular synapse instability and functional abnormalities

Dynactin subunit 1 is the largest subunit of the dynactin complex, an activator of the molecular motor protein complex dynein. Reduced levels of DCTN1 mRNA and protein have been found in sporadic amyotrophic late...

Source: Molecular Neurodegeneration - July 10, 2019 Category: Neurology Authors: Val érie Bercier, Jeffrey M. Hubbard, Kevin Fidelin, Karine Duroure, Thomas O. Auer, Céline Revenu, Claire Wyart and Filippo Del Bene Tags: Research article Source Type: research