Three new diterpenoid alkaloids from Delphinium naviculare var. lasiocarpum W. T. Wang

Publication date: October 2019Source: Phytochemistry Letters, Volume 33Author(s): Wen-Juan Xue, Bo Zhao, Jiang-Yu Zhao, Sh. Sh. Sagdullaev, Haji Akber AisaAbstractThree new diterpenoid alkaloids, designated naviconine (1), naviculine (2) and naviconitine (3), together with five known diterpenoid alkaloids (4)–(8) were isolated from the whole plant of Delphinium naviculare var. lasiocarpum W. T. Wang. The structures of the new compounds were established on the basis of spectroscopic analyses including HR-ESI-MS, 1D and 2D NMR analyses. All of the compounds were evaluated in vitro for cytotoxicity against HT-29, MDA-MB-231 and HeLa cancer cell lines using the MTT method.Graphical abstract
Source: Phytochemistry Letters - Category: Chemistry Source Type: research