4‐O‐methylhonokiol, a PPARγ agonist, inhibits prostate tumour growth: p21‐mediated suppression of NF‐κB activity

Conclusions and ImplicationMH inhibits growth of human prostate cancer cells through activation of PPARγ, suppression of NF‐κB and arrest of the cell cycle. Thus, MH might be a useful tool for treatment of prostate cancer.

Source: British Journal of Pharmacology - February 20, 2013 Category: Drugs & Pharmacology Authors: NJ Lee, JH Oh, JO Ban, JH Shim, HP Lee, JK Jung, BW Ahn, DY Yoon, SB Han, YW Ham, JT Hong Tags: Research Paper Source Type: research