Overview of molecular mechanisms involved in herbal compounds for inhibiting osteoclastogenesis from macrophage linage RAW264.7.

Overview of molecular mechanisms involved in herbal compounds for inhibiting osteoclastogenesis from macrophage linage RAW264.7.
Curr Stem Cell Res Ther. 2019 Jul 03;:
Authors: He G, Ma R
Abstract
Differentiation from RAW264.7 cells to osteoclasts rely on many signaling pathways, such as NF-κB, MAPK, Akt and others. However, the specific underlying mechanisms are not clear. Recently, much works have focused on the inhibitory effects of plant derived compounds in the differentiation from RAW264.7 to osteoclasts. However, the specific mechanisms remain unclear. In this paper, we summarize a lot of plant derived compounds which exert blocking effect on the progression of differentiation via signaling pathways.
PMID: 31269885 [PubMed - as supplied by publisher]

Source: Current Stem Cell Research and Therapy - July 2, 2019 Category: Stem Cells Authors: He G, Ma R Tags: Curr Stem Cell Res Ther Source Type: research