Serum C-terminal cross-linking telopeptide level as a predictive biomarker of osteonecrosis after dentoalveolar surgery in patients receiving bisphosphonate therapy: Systematic review and meta-analysis.

CONCLUSIONS AND PRACTICAL IMPLICATIONS: The use of CTX levels to diagnose MRONJ risk after dental procedures in patients receiving BP is not justified. The cutoff of 150 pg/mL in serum CTX levels is not predictive of MRONJ. Further studies are needed to develop other reliable biomarkers. PMID: 31256803 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31256803?dopt=Abstract

Source: Journal of the American Dental Association - July 2, 2019 Category: Dentistry Tags: J Am Dent Assoc Source Type: research