The burden of hepatitis E among patients with haematological malignancies: A retrospective European cohort study

The hepatitis E virus (HEV), the causative agent of hepatitis E, is a member of the Hepeviridae family that includes enterically-transmitted, small, non-enveloped positive-sense RNA viruses that can infect mammals (Orthohepevirus A, C and D), birds (Orthohepevirus B) and trout (Piscihepevirus). There are 4 major HEV genotypes (HEV-1 to HEV-4) that can infect humans.1 HEV is predominately transmitted by contaminated water in low-income countries (mostly HEV-1 and HEV-2) and by contaminated meat and offal that originate from HEV-infected animals (HEV-3 and HEV-4) in high-income countries.

Source: Journal of Hepatology - May 16, 2019 Category: Gastroenterology Authors: Johann von Felden, Laurent Alric, Sven Pischke, Celia Aitken, Stefan Schlabe, Ulrich Spengler, Maria Teresa Giordani, Paul Schnitzler, Dominik Bettinger, Robert Thimme, Alienor Xhaard, Mascha Binder, Francis Ayuk, Ansgar W. Lohse, Jan J. Cornelissen, Robe Tags: Research Article Source Type: research