CB1 receptor antagonism in capuchin monkeys alters social interaction and aversive memory extinction

ConclusionTaken together, these results suggest that CB1r antagonism induces social deficits without increasing anxiety levels and impairs the extinction of aversive memories. This behavioral profile in monkeys underscores the potential involvement of eCS signaling in the deficits observed in autism spectrum disorders.
Source: Psychopharmacology - Category: Psychiatry Source Type: research