Antimicrobial stewardship impact on Pseudomonas aeruginosa susceptibility to meropenem at a tertiary pediatric institution

Publication date: Available online 26 June 2019Source: American Journal of Infection ControlAuthor(s): Jeremy S. Stultz, Sandra R. Arnold, Chasity M. Shelton, Bindiya Bagga, Kelley R. LeeAn antimicrobial stewardship program was implemented throughout 2012 at a tertiary pediatric institution with guideline development preceding prospective audit and feedback starting in 2013. Meropenem use decreased over 62% during the next 5 years. Non-cystic fibrosis Pseudomonas aeruginosa isolate susceptibility to meropenem increased from 89% in 2011 to 98% in 2017 (P < .001) and correlated with meropenem use the preceding year (Rs: −0.78, P = .008).
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research