Screening for monogenic diabetes in primary care

In the 1960s Fajan came across a mild, asymptomatic variant of diabetes occurring in non-obese children, adolescents, and young adults as part of a study aimed at determining the normal range of the oral glucose tolerance test (OGTT1) [1]. Tattersall later reported three similar families showing characteristics of atypical non autoimmune diabetes with a dominant familial inheritance pattern. Tattersall went on to describe the difference between classical ‘juvenile-onset’ and ‘maturity-onset’ diabetes, the latter subtype being distinguished by successful management with sulphonylureas [2].
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Review Source Type: research