Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and the Emerging Osteopathic Approach: A Narrative Review.

Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and the Emerging Osteopathic Approach: A Narrative Review. J Am Osteopath Assoc. 2019 Jul 01;119(7):446-455 Authors: Larrimore C, Ramnot A, Jaghab A, Sarduy S, Guerrero G, Troccoli P, Hilton K, Bested A Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating syndrome of unknown origin, characterized by profound postexertional malaise and fatigue, unrefreshing sleep, cognitive impairments, immune dysfunction, pain, autonomic dysfunction, and neuroendocrine symptoms. Although ME/CFS is well documented within the medical literature, it remains difficult to diagnosis and manage. Some of the current challenges include an absence of diagnostic markers, differing diagnostic criteria, and an overall lack of awareness within the medical community. As a result, patients are often frustrated by the difficulties in acquiring a diagnosis and from the overall lack of available treatments. In an effort to increase awareness, this review discusses disease pathophysiology, clinical presentation, and treatment options, while also highlighting the benefits of an osteopathic approach. PMID: 31233110 [PubMed - in process]
Source: Journal of the American Osteopathic Association - Category: Complementary Medicine Tags: J Am Osteopath Assoc Source Type: research

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ConclusionsNon-specific symptoms including headache, fatigue and dizziness feature prominently in serious AE reports from females in Denmark. Our analysis identified a cluster of reports, likely media stimulated, with a focus on symptoms of CFS and POTS. PMID: 31088598 [PubMed - in process]
Source: Euro Surveill - Category: Infectious Diseases Authors: Tags: Euro Surveill Source Type: research
Rui Yan1, ShiWan Tao1, HaiYan Liu1, Yu Chen1, JiaBo Shi1, YuYin Yang1, RongXin Zhu1, ZhiJian Yao1,2* and Qing Lu3,4*1Department of Psychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China2Nanjing Brain Hospital, Medical School of Nanjing University, Nanjing, China3School of Biological Sciences and Medical Engineering, Southeast University, Nanjing, China4Child Development and Learning Science, Key Laboratory of Ministry of Education, Nanjing, ChinaBackground: Major depressive disorders often involve somatic symptoms and have been found to have fundamental differences from non-somatic depressi...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
CONCLUSIONS: At the moment, ozone therapy seems a treatment that, also because without any side effect, is possible to be proposed to patients with fibromyalgia that are not obtaining adequate results from other available treatments and it can be considered as complementary/integrative medicine. PMID: 30840304 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Conclusion: This is the first investigation of the presentation of CFS in the ED and indicates the importance of orthostatic intolerance as the most frequent acute cause for a visit. The self-report CFS questionnaire may be useful as a screening instrument in the ED. Education of ED staff about modern concepts of CFS is necessary to improve patient and staff satisfaction. Guidance is provided for the diagnosis and treatment of CFS in these challenging encounters. PMID: 30666170 [PubMed]
Source: Pain Physician - Category: Anesthesiology Authors: Tags: Open Access Emerg Med Source Type: research
ConclusionSelf-reporting and clinical scrutiny are complementary. Structured questionnaires increase the range of predictive variables and should be utilized routinely to facilitate clinicians' quest for the correct diagnosis.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
CONCLUSION: Self-reporting and clinical scrutiny are complementary. Structured questionnaires increase the range of predictive variables and should be utilized routinely to facilitate clinicians' quest for the correct diagnosis. PMID: 30578096 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - Category: Neurology Authors: Tags: Epilepsy Behav Source Type: research
Research suggests body ’s response to infection may be responsible for onset of CFSAn overactive immune response appears to be a trigger for persistent fatigue, say researchers in a study that could shed light on the causes of chronic fatigue syndrome.Chronic fatigue syndrome (CFS) is a debilitating long-term condition in which individuals experience exhaustion that is not helped by rest, as well as pain, mental fogginess and trouble with memory and sleep. It is also known as myalgic encephalomyelitis (ME).Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: ME / Chronic fatigue syndrome Health Science Health policy Medicine Source Type: news
This study used data of LifeLines, a general population cohort in which 1.0% (n=943, 63.7% female, age 44.9 (SD 11.6) years) reported CFS, 3.0% (n=2,714; 91.6% female; age 48.4 (SD 10.7) years) reported FMS, and 95.7% (n=87,532; 57.9% female; age 44.3 (SD 12.4) years) reported neither CFS nor FMS. Physical activity, sleep duration, and symptom severity were assessed by questionnaires and analysed using ANCOVA and regression analyses, adjusted for age, sex, body mass index, smoking, and educational level. Results: Patients with CFS and FMS had significantly lower physical activity scores (8834 ± 5967 and 8813 &p...
Source: Pain Research and Management - Category: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is arguably the last major disease we know almost nothing about. It is a multi-systemic illness of unknown etiology affecting millions of individuals worldwide, with the capacity to persist for several years. ME/CFS is characterized by disabling fatigue of at least 6 months, accompanied serious fatigue and musculoskeletal pain, in addition to impaired short-term memory or concentration, and unrefreshing sleep or extended post-exertional. While the etiology of the disease is still debated, evidence suggest oxidative damage to immune and hematological systems as one...
Source: Blood - Category: Hematology Authors: Tags: 101. Red Cells and Erythropoiesis, Structure and Function, Metabolism, and Survival, Excluding Iron Source Type: research
Chronic Fatigue Syndrome, also known as Myalgic Encephalomyelitis (CFS/ME) is a complex and extremely debilitating chronic medical condition [1]. Its etiology remains unknown. No clinically established diagnostic tests exist; nor are any effective FDA-approved drugs available for treatment currently. Its symptoms are persistent disabling fatigue for more than six months and a constellation of symptoms such as multi-joint pain, myalgia, unrefreshing sleep, impaired memory and/or concentration, new headaches, anxiety/depression, autonomic dysfunction and post-exertional malaise that does not improve with rest.
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - Category: Biomedical Science Authors: Source Type: research
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