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Source: Journal of Pain and Symptom Management - Category: Palliative Care Source Type: research

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Source: Journal of Pain Research - Category: Anesthesiology Tags: Journal of Pain Research Source Type: research
Condition:   Pain, Postoperative Interventions:   Procedure: saphenous nerve block;   Procedure: popliteal plexus block;   Drug: Plain bupivacaine;   Drug: 0.05 mg epinephrine Sponsor:   Fayoum University Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Background: Many of those aging with HIV suffer from distal neuropathic pain (DNP) due to HIV-associated sensory neuropathy (HIV-SN). Prior studies have linked chronic pain conditions to a variant of the catechol-O-methyltransferase (COMT), Val158Met. This variant confers reduced enzymatic activity and results in higher synaptic dopamine levels. Here we examined the role of Val158Met as a predictor of DNP in HIV-SN. Methods: In 1044 HIV-infected individuals enrolled in CNS HIV Antiretroviral Therapy Effects Research, an observational study across six US institutions, we characterized the relationship between Val158Met...
Source: AIDS - Category: Infectious Diseases Tags: CLINICAL SCIENCE Source Type: research
Written by Pendell MeyersA female in her mid 60s with history of SVT and HTN presented with sudden onset 3/10 chest tightness while lying in bed in the early morning. She had nausea and diaphoresis with this event, as well as tightness between her scapula, and a loose bowel movement.Here is her initial ECG at presentation to the ED at time zero (no prior available):What do you think?Sinus rhythm with significant downsloping STD in V1-V3, maximal in V1-V2. There is also subtle STE in V6 with large-area T-wave with straight/convex ST segment morphology. The T-waves in the inferior leads could be large if a prior ECG wer...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
ConclusionsTo date the methods of placebo/sham control and blinding in RCTs have been poorly reported, leading to concerns about the validity and replicability of the findings. Important aspects that need to be clearly reported in the design of placebo ‐/sham‐controlled RCTs of SCS include the transparent reporting of stimulation programming parameters, patient position during perception threshold measurement, management of the patient handheld programmer, frequency of recharging, and assessment of the fidelity of blinding.
Source: Neuromodulation: Technology at the Neural Interface - Category: Biotechnology Authors: Tags: Review Article Source Type: research
ConclusionIn this pioneering attempt, the document lays down structured, expert consensus-based statements to guide and align practitioners on the appropriate use of IAHA in the Indian setting.FundingDr. Reddy ’s Laboratories Ltd.
Source: Pain and Therapy - Category: Anesthesiology Source Type: research
Fear of pain resonates with most people, in particular in relation to dying. Despite this, there are still people dying with unrelieved pain.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
People with metastatic cancers experience poor quality of life (QoL), fatigue, and decreased physical function. Exercise improves these symptoms in the curative setting, but the efficacy and safety of exercise in the metastatic setting is uncertain.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
ConclusionsOur scoping review found the majority of published articles described chiropractic services in the active duty military in the US setting. Recent RCTs suggest a benefit of including chiropractic care to usual medical care in managing back pain in active duty military. Yet despite reported benefits in Australia, Canada, and the US, there is a need for further qualitative, descriptive, and clinical trial data worldwide to inform the role of chiropractic services in active duty military.
Source: Chiropractic and Manual Therapies - Category: Complementary Medicine Source Type: research
ConclusionThe evidence obtained shows LLLT has a positive effect in controlling diabetic neuropathic pain.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
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