Treatment with metformin in twelve patients with Lafora disease

Lafora disease (LD) is a rare, lethal, progressive myoclonus epilepsy for which no targeted therapy is currently available. Studies on a mouse model of LD showed a good response to metformin, a drug with a wel...

Source: Orphanet Journal of Rare Diseases - June 21, 2019 Category: Internal Medicine Authors: Francesca Bisulli, Lorenzo Muccioli, Giuseppe d ’Orsi, Laura Canafoglia, Elena Freri, Laura Licchetta, Barbara Mostacci, Patrizia Riguzzi, Federica Pondrelli, Carlo Avolio, Tommaso Martino, Roberto Michelucci and Paolo Tinuper Tags: Letter to the Editor Source Type: research