Low levels of pannexin ‐1 in Behçet’s syndrome

AbstractObjectiveBeh çet's syndrome (BS) is a chronic, multisystemic and inflammatory syndrome. In our study, we aimed to compare the initiator, effector and inflammatory caspases and pannexin channel protein, which is thought to have an activity in inflammation, in the inflammatory process of BS, with healthy subjects , to investigate their level in patients and their relationship with the clinical findings.MethodForty ‐six patients who were under follow‐up for BS in the Sivas Cumhuriyet University Medical Faculty Department of Internal Diseases, Rheumatology Unit, between January 2017 and June 2017 and 44 healthy controls (HC) who did not have any rheumatic, systemic or metabolic diseases, were enrolled in th is study.ResultsThe mean serum pannexin ‐1 level was 6.36 (4.21‐527.2) pg/mL in the BS group and 255.8 (5.38‐2000) pg/mL in the HC group. Serum pannexin‐1 levels were statistically significantly lower in the BS group (P 
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: ORIGINAL ARTICLE Source Type: research

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ConclusionsThe use of adhesive can improve masticatory performance of new complete dentures users with normal mandibular ridges in the initial adaptation period up to 60 days after insertion. For resorbed ridges subjects, the use of adhesive had a negative impact on masticatory discomfort/disability OHRQoL at 30 days after insertion.
Source: Journal of Prosthodontic Research - Category: Dentistry Source Type: research
ConclusionEATP lowered the serum uric acid level and increased the urine uric acid level through excretion, which is useful in the treatment of gout. Hence the EATP was found to be helpful in the treatment of gout.
Source: Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
Publication date: Available online 21 August 2019Source: Journal of Ginseng ResearchAuthor(s): Moon Young Park, Se Jik Han, Donggerami Moon, Sangwoo Kwon, Jin-Woo Lee, Kyung Sook KimAbstractBackgroundRed ginseng contains components that can be used in skincare to delay the aging process, including microelements, vitamins, essential oils, and fatty acids. We investigated the effects of red ginseng treatment on skin elasticity by assessing cellular stiffness and measuring collagen protein synthesis.MethodsHuman dermal fibroblasts were treated with red ginseng, and the resulting changes in stiffness were investigated using at...
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research
ConclusionDifferentially expressed in tumors, PLA2G4A, PRKCB, PIK3R1, KDR, PLA2G1B and PTGS2 are potential therapeutic targets of Yupingfengsan in the treatment of LAD, and MAPK, VEGF and ErbB signaling pathways are involved.
Source: European Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research
Publication date: Available online 22 August 2019Source: Journal of Cardiology CasesAuthor(s): Shohei Kataoka, Ken Kato, Hiroyuki Tanaka, Tamotsu TejimaAbstractIt is challenging to perform ablation of ventricular tachycardia (VT) from the left ventricle (LV) in patients without catheter access to the LV. A 50-year-old man was referred to our hospital for VT. He underwent mechanical aortic and mitral valve replacement for infective endocarditis and embolic myocardial infarction in the left ventricular inferior wall during a surgery. Anti-arrhythmia drugs (AADs) such as sotalol and bisoprolol were initiated and implantable c...
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
Publication date: Available online 22 August 2019Source: Journal of Cardiology CasesAuthor(s): Takashi Ando, Hiroshi Okada, Makoto Takeda, Tomio UmemotoAbstractPeriaortitis is one of the less common manifestations of the aorta pathology. Periaortitis mostly arises from the outer layers of the abdominal aorta and iliac arteries. However, other large arteries may also be involved, but rarely the thoracic aorta. Here we present a successful conservative treatment using prednisolone therapy for periaortitis of the aortic arch which shows various clinical symptoms.
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
Publication date: October 2019Source: Interventional Cardiology Clinics, Volume 8, Issue 4Author(s): Julian Yeoh, Jonathan Hill
Source: Interventional Cardiology Clinics - Category: Cardiology Source Type: research
Publication date: October 2019Source: Interventional Cardiology Clinics, Volume 8, Issue 4Author(s): David A. Power, Paul Guedeney, George D. Dangas
Source: Interventional Cardiology Clinics - Category: Cardiology Source Type: research
Publication date: October 2019Source: Interventional Cardiology Clinics, Volume 8, Issue 4Author(s):
Source: Interventional Cardiology Clinics - Category: Cardiology Source Type: research
Publication date: October 2019Source: Interventional Cardiology Clinics, Volume 8, Issue 4Author(s):
Source: Interventional Cardiology Clinics - Category: Cardiology Source Type: research
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