Reflectance Confocal Microscopy as a Novel Method to Assess Carcinoma and Normal Skin Response to Electronic Skin Surface Brachytherapy: Preliminary Results from a Prospective Clinical Trial

Brachytherapy is an effective treatment for many keratinocyte carcinomas. However, the response to treatment is typically a clinical assessment and may be challenging to perform. The microscopic effect of ionizing radiation therapy on carcinoma as well as normal skin has never been well characterized. Reflectance confocal microscopy (RCM) is a novel in vivo skin imaging technique which may enable a better understanding of the response to brachytherapy at the histologic level. As part of an ongoing prospective clinical trial of electronic skin surface brachytherapy (ESSB), we performed RCM before and at specified times after treatment.
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research