Insights into IgM-mediated complement activation based on in situ structures of IgM-C1-C4b [Immunology and Inflammation]

We present cryoelectron tomography structures of IgM, C1, and C4b complexes formed on antigen-bearing lipid membranes by normal human serum at...

Source: Proceedings of the National Academy of Sciences - June 10, 2019 Category: Science Authors: Thomas H. Sharp, Aimee L. Boyle, Christoph A. Diebolder, Alexander Kros, Abraham J. Koster, Piet Gros Tags: Biological Sciences Source Type: research