Medial Premotor Cortex Shows a Reduction in Inhibitory Markers and Mediates Recovery in a Mouse Model of Focal Stroke [Basic Sciences]

Conclusions— We conclude that with training, AGm can reorganize after a focal motor stroke and serve as a new control area for prehension. Reduced inhibition may represent a marker for reorganization or it is necessary for reorganization to occur. Our mouse model, with all of the attendant genetic benefits, may allow us to determine at the cellular and molecular levels how behavioral training and endogenous plasticity interact to mediate recovery.
Source: Stroke - Category: Neurology Authors: Tags: Animal models of human disease, Acute Cerebral Infarction, Rehabilitation, Stroke Basic Sciences Source Type: research