Tools for visualizing cell-cell 'interactomes'

Tools for visualizing cell-cell 'interactomes' Curr Opin Chem Biol. 2014 Dec 1;24C:121-130 Authors: Porterfield WB, Prescher JA Abstract Cellular communication drives diverse aspects of organismal biology ranging from immune function to memory formation. The mechanisms by which cells transact information in vivo, though, are not completely understood. This is due, in part, to a lack of tools for observing collections of cells in their native habitats. New optical probes are being crafted to image networks of cell-cell interactions (i.e., 'interactomes') in tissues and live organisms. Examples of these probes-and their use in visualizing cell contacts and macroscopic cell networks-are highlighted. PMID: 25461730 [PubMed - as supplied by publisher]
Source: Current Opinion in Chemical Biology - Category: Biochemistry Authors: Tags: Curr Opin Chem Biol Source Type: research