Scalp EEG High Frequency Oscillations as a Biomarker of Treatment Response in Epileptic Encephalopathy with Continuous Spike-and-Wave during Sleep (CSWS)

The EEG phenomenon of ESES was first described in 1971 in a case series of 6 children with epilepsy who were found to have continuous spike-wave discharges in non –rapid eye movement sleep, with resolution upon awakening. [1] CSWS is a specific clinical syndrome, defined in 1989 as an epileptic encephalopathy during childhood that shows continuous EEG abnormalities during non-REM sleep (often shows ESES), in association with a variety of seizure types, incl uding nocturnal convulsions, atypical absence seizures, and epileptic negative myoclonus.
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research